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2 Popular Weight Loss Pills and Supplements Reviewed

The Complete Herbal Guide / Everyday Solutions  / 2 Popular Weight Loss Pills and Supplements Reviewed

2 Popular Weight Loss Pills and Supplements Reviewed

Today, we will compare two most popular weight loss drugs, Alli and Lipozene, and find out how they work and which one is safer by comparing their ingredients and effectiveness.


Orlistat is a pharmaceutical drug, sold over-the-counter under the name Alli, and under prescription as Xenical.  The main component of Alli is orlistat, the white powder-like substance that inhibits pancreatic and gastric lipases thus reducing weight.

How it works

This weight loss pill works by inhibiting the breakdown of fat in the gut, making you take in fewer calories from fat.


According to a big review of 11 studies, orlistat can increase weight loss by 6 pounds

Weight loss is the main one. Orlistat significantly re (2.7 kg) compared to a dummy pill (13).

The benefits of Alliduces weight by breaking down the food that gets to the intestine by inhibiting the enzyme called pancreatic lipase. When you take Alli, you basically reduce the amount of lipase in your intestine, which means that the food you consume won’t turn into fatty acids. This reduces the number of calories you consume daily.

Other benefits

Orlistat has been shown to reduce blood pressure slightly and reduced the risk of developing type 2 diabetes by 37% in one study (1415).

Side effects

According to Alli review on Expertratedreviews, it’s the side effects that occur when orlistat removes fat from the body. These effects create discomfort due to increased flatulence, sudden diarrhea, or decreased vitamin absorption by the body.  This drug has many digestive side effects, including loose, oily stools, flatulence, frequent bowel movements that are hard to control, and others. It may also contribute to the deficiency in fat-soluble vitamins, such as vitamins A, D, E and K.

To minimize the side effects, it is usually recommended to follow a low-fat diet.

Interestingly, a low carb diet (without drugs) has been shown to be as effective as both orlistat and a low-fat diet combined (16).


This drug works a bit differently. In fact, the principles that make Lipozene work are still not clear. But according to some clinical trials, the main component of this drug called glucomannan (a natural fiber) reduces the daily intake of calories by faking the sense of fullness. In other words, it suppresses your appetite. It also contains other ingredients, such as green tea, vitamins, and koala nut, however, glucomannan remains Lipozene’s only active ingredient.

Now, Lipozene is supported by clinical trials. Besides, you can check the drug’s efficiency by obtaining a free sample. But the drug’s official website doesn’t provide potential customers with enough information on the product, and the drug itself doesn’t burn fat, although its creators claim it does. All this becomes a reason for negative feedbacks.

There is also not so many information concerning Lipozene’s ingredients, which makes this drug risky because of unpredictable side effects. You can’t be sure what consequences you may come across taking Lipozene.

Which one is better?

To end the discussion, we just need to note that Lipozene isn’t approved by FDA due to its mysterious composition. Alli also has its drawbacks, with negative side effects being the main ones. Nevertheless, clinical trials have shown that Alli is both effective and stable. The results are clearly visible after a short time period. And Alli is approved by FDA, which means that it’s safer than Lipozene.



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Stacey Chillemi


I am on a mission to transform the health of millions worldwide. Check out my website at staceychillemi.com. I am a popular and recognizable health and lifestyle reporter and expert, columnist and health host. Author of The Complete Guide to Natural Healing and Natural Remedies for Common Conditions, along with 20 other published books. I am the founder of The Complete Herbal Guide and a recognized health and natural remedies expert, with over 20 years in practice as a Health Coach. I write for the Huffington Post, Huff Post, Thrive Global and Medium (Owned by Arianna Huffington). I have been a guest on the Dr. Oz Show, local news, and numerous radio shows. My focus is on natural healing, herbal remedies, alternative methods, self-motivation, food for medicine, nutrition, fitness, natural beauty remedies and the power of positive thinking.